EFFECTS OF CCPA GENE DEFICIENCY IN LACTOBACILLUS DELBRUECKII SUBSP. BULGARICUS UNDER AEROBIC CONDITIONS AS ASSESSED BY PROTEOMIC ANALYSIS

Effects of ccpA gene deficiency in Lactobacillus delbrueckii subsp. bulgaricus under aerobic conditions as assessed by proteomic analysis

Abstract Background Aerobic growth provides benefits in biomass yield and stress tolerance of Lactobacillus delbrueckii subsp.bulgaricus (L.bulgaricus).Catabolite control protein A (CcpA) is a master regulator involved in the aerobic and anaerobic growth, metabolic production and stress response in L.bulgaricus, but its potential molecular mechanis

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Engineering Organ-on-a-Chip to Accelerate Translational Research

We guide the use of organ-on-chip technology in tissue engineering applications.Organ-on-chip technology is a form of microengineered cell culture platform that elaborates the in-vivo like organ or tissue microenvironments.The organ-on-chip platform consists of microfluidic channels, cell culture chambers, and stimulus sources that emulate the in-v

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Extensively Drug-Resistant Typhoid Outbreak in Pakistan, Experience at a Tertiary Care Hospital in Lahore; A Tip of An Iceberg

Objective: To provide a laboratory-based surveillance report of typhoid fever cases diagnosed at a tertiary care hospital in Lahore during the ongoing outbreak.Study Design: Cross-sectional study.Place and Duration of Study: Department of Microbiology, Combined Military Hospital, Lahore Pakistan, from Mar 2018 to Jun 2019.Methodology: All positive

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Myrtucommulones and Related Acylphloroglucinols from Myrtaceae as a Promising Source of Multitarget SARS-CoV-2 Cycle Inhibitors

The LABEXTRACT plant extract bank, featuring diverse members of the Myrtaceae family from Brazilian hot spot regions, provides a promising avenue for bioprospection.Given the pivotal roles of the Spike protein and 3CLpro and PLpro proteases in SARS-CoV-2 infection, this study delves into the correlations between the Myrtaceae species from the Atlan

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